Thursday 30th April.

9:00 Plenary Session Diabetes and Melioidosis

9:00 Prof Sarah Wild - Changing Global Diabetes Epidemiology and possible implications for melioidosis risk

9:40 Prof Susie Dunachie - How does Diabetes cause increased risk of melioidosis?

10:30 Break

11:00 Clinical Microbiology and Diagnostics

11:00 Paul Keim - Ten years later: Investigating Accidental Melioidosis Infections at a Primate Center

11:25 Dao Thi Ngoc Huyen - The clinical, laboratory features and the outcome of patients with Burkholderia pseudomallei infection at University Medical Center Ho Chi Minh city from 2018 to 2022

11:45 Koukeo Phommasone - Outcomes of patients with suspected or confirmed melioidosis: a multi-national, multicenter, observational study

12:00 Chimanjita Phukan - Capacity building for Melioidosis in an underdiagnosed region of North-East of India

12:20 Solohery Lalaina Razafimahatratra - Advancing melioidosis diagnosis and immunological research in a low-resource setting

12:40 Vanina Guernier - Environmental Burkholderia pseudomallei along a gradient of anthropization in Thailand: comparison of detection methods, factors of occurrence, and microbiome signature.

13:00 Lunch and Posters

13:45 Epidemiology, AMR and Surveillance

13:45 Emma Birnie - Invited Speaker: TBA

14:15 Saika Farook - Melioidosis in Bangladesh: pin pointing the source utilizing an improved culture technique

14:30 Sophie Guillier - Evolutionary convergence and structural characterisation of an allosteric DHFR mutation conferring trimethoprim resistance in Burkholderia thailandensis

14:50 Arin Wongprommoon - Genome-wide association study of Burkholderia pseudomallei in northeast Thailand identifies bacterial variants associated with melioidosis mortality

15:10 Break

15:30 Jayde Hopkins - Melioidosis in the Desert: An Australian Investigation

15:50 Phumrapee Boonklang - Genomic and transcriptomic profiles of a melioidosis cohort from Northeast Thailand

16:10 Sukanta Chowdhury - Melioidosis in Bangladesh: An Underrecognized Public Health Burden Revealed by Clinical Surveillance

16:30 Ayush Gupta - Whole genome sequencing analysis of temporally linked clinico-environmental Burkholderia pseudomallei isolates in a landlocked region of central India

16:50 Malti Dadheech - Molecular epidemiology of clinical Burkholderia pseudomallei isolates from a traditionally non-endemic region of central India

17:10 Poster Session

 Conference Dinner (with transport to and from)

Friday 1st May

 Vaccines and Therapeutics

09:30 Jeremy Aboagye Invited Speaker:- Fortifying the Frontlines: a vaccine strategy inducing broad mucosal immunity against Burkholderia pseudomallei

09:55 Julen Tomás Cortázar - Immunogenicity of BpOmpW and BpPhbB based next-generation mono- and multivalent vaccines

10:15 Neha Gupta - Next-Gen Solutions for Burkholderia pseudomallei

10:35 Jason Thornton - Multivalent Outer Membrane Vesicle (OMV) Vaccine for Melioidosis and Glanders

10:55 Jason Ladner - Finely characterizing antibody responses against the entire Burkholderia pseudomallei proteome using highly multiplexed serology

11:15 Break

11:45 Jelmer Savelkoel - Movie: Soil Fever

12:10 Host-pathogen interactions and Immunology I

12:10 Dammalage Lasanthi Bhagya Piyasiri - Association of diabetes mellitus with the disease entity and clinical parameters in culture positive melioidosis; a decade long database analysis

12:35 Madeleine Moule - Exploring a new role for multinucleated giant cell formation in systemic dissemination

13:00 Lunch and Posters

14:00 Host-pathogen interactions and Immunology II

14:00 Narisara Chantratita - Integrated host–pathogen omics to predict clinical outcomes and antibiotic resistance in melioidosis

14:25 Priyanka Abraham - Uncovering the long-term impact of melioidosis infection on immune health in people with diabetes by single cell transcriptomic profiling

14:45 Barbara Kronsteiner-Dobramysl - Patients with acute melioidosis show high levels of anti-cytokine autoantibodies

15:05 Apichai Tuanyok - A P2-like prophage lipoprotein regulates the balance between lysogeny, induction, and superinfection in Burkholderia pseudomallei.

15:25 Break

15:45 Isanawidya Hikmah Paramita - Features of Unconventional T Cells Associated with Survival in Acute Melioidosis with Type 2 Diabetes Mellitus

16:05 Chiranjay Mukhopadhyay - Immunometabolic Signatures Distinguish Melioidosis from Tuberculosis in Patients with Diabetes Mellitus: Insights from Clinical Profiling and Experimental Models

16:25 Anucha Preechanukul - Dual function of NK cells in regulating Burkholderia pseudomallei-specific CD8 T cells via a HLA-C-dependent manner

16:45 Final remarks and Finish

*Length of talks vary, but all talk time slots allow 5 min for questions.